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Gastroenterology Research and Practice
Volume 2017 (2017), Article ID 8349150, 11 pages
https://doi.org/10.1155/2017/8349150
Review Article

Hepatitis C Virus and Nonliver Solid Cancers: Is There an Association between HCV and Cancers of the Pancreas, Thyroid, Kidney, Oral Cavity, Breast, Lung, and Gastrointestinal Tract?

1New York Medical College and Westchester Medical Center, 100 Woods Road, Valhalla, NY 10595, USA
2Bristol-Myers Squibb, 5 Research Pkwy, Wallingford, CT 06492, USA

Correspondence should be addressed to Saad Qadwai

Received 30 December 2016; Revised 28 March 2017; Accepted 3 April 2017; Published 3 May 2017

Academic Editor: Haruhiko Sugimura

Copyright © 2017 Saad Qadwai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hepatitis C virus (HCV) is known for its oncogenic potential and has been found to be associated with hepatocellular carcinoma (HCC) and non-Hodgkin lymphoma. It has also been postulated that HCV may play a role in the development of other extrahepatic solid tumors of other organs of the body since it has been isolated from the vessel wall, kidney, and oral mucosa. In this article, we have reviewed epidemiological studies that have been done to look into the relationship of HCV with nonliver solid cancers of the pancreas, thyroid, renal, oral cavity, breast, and lung and nonpancreatic gastrointestinal cancers. Based on this review, HCV might be associated with an increased risk of renal cell and lung cancers.