Metformin and Diammonium Glycyrrhizinate Enteric-Coated Capsule versus Metformin Alone versus Diammonium Glycyrrhizinate Enteric-Coated Capsule Alone in Patients with Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
Table 3
Comparisons within groups and between groups in patients with T2DM and NAFLD at 24 weeks.
Group 1 ()
Group 2 ()
Group 3 ()
value
value+
value+
value+
value
value
value
Weight (kg)
<0.001
<0.001
<0.001
0.008
0.341
0.032
0.002
BMI (kg/m2)
<0.001
<0.001
<0.001
0.004
0.689
0.007
0.002
ALT (U/L)
<0.001
<0.001
<0.001
<0.001
<0.001
<0.001
0.044
AST (U/L)
0.016
<0.001
<0.001
<0.001
<0.001
<0.001
0.049
GGT (U/L)
<0.001
<0.001
<0.001
<0.001
0.014
<0.001
0.048
CB (µmol/L)
<0.001
<0.001
<0.001
0.131
0.495
0.158
0.777
TB (µmol/L)
<0.001
0.008
<0.001
0.058
0.017
0.219
0.261
TG (mmol/L)
<0.001
<0.001
<0.001
0.004
0.999
0.009
0.003
TC (mmol/L)
<0.001
0.013
<0.001
<0.001
0.402
0.002
<0.001
HDL (mmol/L)
<0.001
0.004
<0.001
0.01
0.492
0.024
0.004
LDL (mmol/L)
0.047
0.288
<0.001
0.007
0.804
0.009
0.004
SF (µg/L)
<0.001
<0.001
<0.001
0.002
0.191
0.027
0.001
HbA1c (%)
<0.001
0.09
<0.001
<0.001
<0.001
0.039
<0.001
FBG (mmol/L)
<0.001
0.071
<0.001
<0.001
0.008
0.034
<0.001
FINS (mU/L)
0.006
0.114
<0.001
<0.001
0.015
0.007
<0.001
HOMA-IR
0.001
0.098
<0.001
<0.001
0.030
0.011
<0.001
CT ratio
<0.001
<0.001
<0.001
<0.001
0.912
0.001
<0.001
Fibroscan
<0.001
<0.001
<0.001
<0.001
0.990
0.001
<0.001
value was calculated by one-factor analysis of variance or the Wilcoxon signed rank test for intergroup comparisons at 24 weeks. value, value, and value were calculated by the paired -test or the Wilcoxon signed rank test for within groups. value for comparisons between group 2 and group 1, value+ for comparisons between group 3 and group 1, and value for comparisons between group 3 and group 2.
