Metformin and Diammonium Glycyrrhizinate Enteric-Coated Capsule versus Metformin Alone versus Diammonium Glycyrrhizinate Enteric-Coated Capsule Alone in Patients with Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus

Table 4

Liver function and lipid Profile in the three groups at baseline and during treatment.

	Baseline	8 weeks	16 weeks	24 weeks
ALT (U/L)
Group 1	86.75 ± 27.59	74.22 ± 29.09	67.19 ± 27.40	63.04 ± 26.80
Group 2	90.79 ± 28.13	51.03 ± 21.18	39.70 ± 14.37	40.45 ± 16.30
Group 3	91.64 ± 28.61	51.80 ± 21.22	34.07 ± 14.55	32.23 ± 16.18
AST (U/L)
Group 1	67.28 ± 34.68	60.19 ± 25.57	56.16 ± 22.66	53.38 ± 29.81
Group 2	69.38 ± 35.79	41.64 ± 15.20	32.98 ± 11.78	32.06 ± 10.41
Group 3	69.60 ± 36.00	43.72 ± 16.35	31.33 ± 13.68	25.91 ± 13.82
GGT (U/L)
Group 1	88.96 ± 43.02	70.71 ± 31.81	64.23 ± 27.85	59.53 ± 32.38
Group 2	90.29 ± 37.12	53.92 ± 19.09	43.68 ± 13.24	43.32 ± 22.63
Group 3	93.27 ± 34.98	59.70 ± 27.20	40.02 ± 116.75	33.57 ± 16.07
CB (µmol/L)
Group 1	5.14 ± 3.10	4.26 ± 2.11	3.51 ± 1.70	3.07 ± 1.80
Group 2	6.52 ± 4.18	4.35 ± 2.58	3.59 ± 1.46	3.60 ± 2.36
Group 3	6.45 ± 3.40	5.63 ± 2.54	3.57 ± 1.79	4.09 ± 3.12
TB (µmol/L)
Group 1	15.77 ± 6.29	13.66 ± 4.46	12.17 ± 3.95	9.81 ± 4.87
Group 2	15.31 ± 6.79	12.76 ± 5.35	11.40 ± 3.36	12.16 ± 4.83
Group 3	17.25 ± 7.72	15.12 ± 4.14	11.78 ± 3.89	11.04 ± 4.92
TG (mmol/L)
Group 1	2.97 ± 1.21	2.08 ± 0.82	1.87 ± 0.92	1.82 ± 0.96
Group 2	3.07 ± 1.04	2.40 ± 0.90	2.02 ± 0.64	1.80 ± 0.78
Group 3	3.24 ± 1.21	2.12 ± 0.80	1.88 ± 0.61	1.33 ± 0.57
TC (mmol/L)
Group 1	6.57 ± 1.71	5.33 ± 1.19	4.79 ± 0.85	5.22 ± 1.22
Group 2	6.39 ± 1.73	5.89 ± 0.87	5.28 ± 1.28	5.44 ± 1.19
Group 3	6.62 ± 1.71	5.65 ± 0.96	4.95 ± 1.18	4.38 ± 1.47
HDL-C (mmol/L)
Group 1	0.91 ± 0.30	0.98 ± 0.28	1.05 ± 0.30	1.14 ± 0.39
Group 2	0.94 ± 0.28	0.98 ± 0.31	1.02 ± 0.33	1.09 ± 0.39
Group 3	0.95 ± 0.28	1.03 ± 0.29	1.15 ± 0.31	1.32 ± 0.35
LDL-C (mmol/L)
Group 1	4.09 ± 1.34	3.94 ± 1.47	3.85 ± 1.64	3.59 ± 1.50
Group 2	3.95 ± 1.02	3.87 ± 1.59	3.72 ± 1.34	3.66 ± 1.50
Group 3	4.15 ± 0.87	3.81 ± 0.59	3.71 ± 1.09	2.80 ± 1.35