Clinical Study

Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial

Table 3

Ulcer evaluations after ESD, and the absence of post-ESD bleeding.

Total ()V group ()E group () value

Ulcer stage after 4 weeks (scar, n)5230.669
Ulcer stage after 8 weeks (scar, n)4624220.42
Shrinkage rate after 4 weeks (%), range95.4 (72.0–100)96.8 (72.0–100)97.5 (75.8–100)0.656
Shrinkage rate after 8 weeks (%)1001001000.257
ESD specimen area (mm2) median (IQR)942.3 (588.8–1452.3)961.8 (707.8–1380.0)880.8 (588.8–1638.8)0.612
Post-ESD bleeding000

IQR: interquartile range (a measure of variability, based on dividing a dataset into quartiles). A value < 0.05 was considered significant. Significant by the Mann–Whitney U test.