Review Article

Pros and Cons of the SeHCAT Test in Bile Acid Diarrhea: A More Appropriate Use of an Old Nuclear Medicine Technique

Table 1

Advantages and disadvantages of the SeHCAT test for BAM.

AdvantagesDisadvantages

Gold standard for the diagnosis of BAM with high sensitivity and specificityRelatively expensive and usually available only at third-level centers
Simple, safe, and well toleratedSeHCAT does not exclude other causes of organic diarrhea
Quantitative evaluation of BAM predicts the response to therapy with BASsThe optimal cutoff level for diagnosis is not yet completely agreed by all centers
More rational use of BASs in relation to possible side effectsDiagnosis of BAM could be empirically obtained with a BAS trial