Prognostic Significance of Blood, Serum, and Ascites Parameters in Patients with Malignant Peritoneal Mesothelioma or Peritoneal Carcinomatosis

Table 5

Univariate and multivariant analysis of the association between potential prognostic factors and survival for all 125 patients with malignant peritoneal effusions.

Prognostic factors	Categories	Patients (n)	Median survival time (months) (95% CI)	value^a	value^b
Sex	Male	49	8.0 (5.3–10.7)	0.131
	Female	76	12.0 (8.9–15.1)
Age (years)	<67	80	11.0 (8.6–13.4)	0.528
	≥67	45	7.0 (3.5–10.4)
Ascites glucose level (mmol/L)	<5.2	65	11.0 (8.5–13.5)	0.770
	≥5.2	60	7.0 (1.7–12.3)
Ascites albumin level (g/L)	<28	65	8.0 (1.4–14.6)	0.990
	≥28	60	12.0(8.8–15.2)
Ascites LDH level (U/L)	<299	62	14.0 (11.79–16.25)	0.015	0.023
	≥299	63	7.0 (4.4–9.6)
Ascites coenocyte numbers (%)	<30	61	12 (11.0–13.0)	0.023
	≥30	64	7 (5.1–8.9)
Ascites monocyte numbers (%)	<70	55	7.0 (5.0–9.0)	0.207
	≥70	70	12.0 (11.1–12.9)
Ascites coenocyte-to-monocyte ratio	<0.43	64	12.0 (10.2–13.8)	0.019
	≥0.43	61	7.0 (5.0–9.0)
Serum albumin level (g/L)	<34	59	8.0 (4.9–11.2)	0.220
	≥34	66	12.0 (9.6–14.4)
Serum-ascites albumin gradient (g/L)	<8.0	62	12.0 (9.1–14.9)	0.765
	≥8.0	63	12.0 (9.7–14.3)
Serum LDH level (range) (U/L)	<210.5	64	14.0 (11.2–16.8)	0.008	0.037
	≥210.5	61	7.0 (4.6–9.4)
Ascites-serum LDH ratio	<1.14	61	12.0 (6.7–17.3)	0.885
	≥1.14	64	12.0 (10.9–13.1)
Blood neutrophil-to-lymphocyte ratio	<3.62	62	12.0 (11.0–13.0)	0.027
	≥3.62	63	7.0 (3.0–11.1)

^aUnivariate analysis: Kaplan–Meier method; ^bmultivariant analysis: Cox regression method.