Research Article

EI24 Suppresses Tumorigenesis in Pancreatic Cancer via Regulating c-Myc

Figure 1

Expression levels of EI24 in PDAC tissues. (a, b) EI24 mRNA and protein expression levels in six pairs of PDAC tissues (T) and adjacent normal tissues (N) detected by RT-qPCR and Western blot analysis, respectively. (c) Immunohistochemical analysis of EI24 expression in pancreatic cancer tissues. Brown color represents positive cytoplasm and nucleus EI24 staining (scale bar represents 50 μm, 200x and 400x magnification). (d) Statistical gram shows that EI24 was downregulated in PDAC tissues (T) than in adjacent normal tissues (N). (e) Statistical analysis showed that EI24 expression was significantly lower in PDAC cells than in normal pancreatic acinus/islands. and , compared with controls.
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