Research Article

Sustained Clinical Efficacy and Mucosal Healing of Thiopurine Maintenance Treatment in Ulcerative Colitis: A Real-Life Study

Table 1

Demographic and clinical characteristics of patients.

Patient

Gender (%)
Female104 (54.1)
Male88 (45.9)
Age, years
Median (range)36 (16–69)
Disease duration, years
Median (range)3.3 (0–31)
Disease extension (%)
Extensive colitis117 (60)
Left-sided colitis75 (40)
Mayo endoscopic subscore (%)
Mayo 116 (9)
Mayo 291 (52)
Mayo 368 (39)
Smoking habit (%)
Yes23 (12)
No/former smoker169 (88)
Indication for starting thiopurines (%)
Steroid dependency111 (58)
Maintenance after a severe attack36 (19)
Frequent relapses45 (23)
Cotreatment with mesalazine (%)175 (91.1)
Duration of thiopurine therapy, months
Median (range)36 (1–210)