Research Article
SHMT2 Overexpression Predicts Poor Prognosis in Intrahepatic Cholangiocarcinoma
Table 2
Univariate analysis of clinicopathological features for overall survival of patients with intrahepatic cholangiocarcinoma.
| Characteristics () | Number | Survival rate (%) | ∗ |
| Gender | | | 0.064 | Female | 31 | 32.3 | | Male | 69 | 34.8 | | Age (years) | | | 0.325 | <60 | 52 | 38.5 | | ≥60 | 48 | 29.2 | | SHMT2 expression | | | 0.030 | Low | 48 | 45.8 | | High | 52 | 23.1 | | Vascular invasion | | | 0.470 | No | 64 | 31.3 | | Yes | 36 | 38.9 | | Tumor number | | | 0.012 | Solitary | 91 | 35.2 | | Multiple | 9 | 22.2 | | Tumor size (cm) | | | 0.484 | ≤5 | 40 | 32.5 | | >5 | 60 | 35.0 | | Pathological grade | | | 0.800 | I | 4 | 50 | | II | 62 | 33.9 | | III | 34 | 32.4 | | T stage | | | <0.001 | T1 | 42 | 40.5 | | T2 | 47 | 34.0 | | T3–T4 | 11 | 9.0 | | N stage | | | 0.888 | N0 | 86 | 33.7 | | N1 | 14 | 35.7 | | Metastasis | | | 0.073 | No | 96 | 35.4 | | Yes | 4 | 0 | | TNM stage | | | 0.058 | I | 34 | 38.2 | | II | 42 | 35.7 | | III–IV | 24 | 25.0 | |
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