Predictive and Prognostic Implications of Mutation Profiling and Microsatellite Instability Status in Patients with Metastatic Colorectal Carcinoma

Table 3

Logistic regression analysis of the factors associated with brain and/or lung metastases in metastatic colorectal cancer patients.

Characteristics	OR	95% CI	value
C-MET expression: negative/weak versus moderate/strong	3.901	2.496–6.098	<0.001
RAS/BRAF genes: all wild-type versus any mutation	4.027	2.551–6.358	<0.001
Constant	0.111

is statistically significant. CI: confidence interval; OR: odds ratio; C-MET: mesenchymal-epithelial transition factor.