Prognostic Analysis of Duodenal Gastrointestinal Stromal Tumors

Table 1

Clinical and pathological features for 55 cases of DGIST associate with disease-free survival (DFS) and overall-survival (OS).

Characteristic	N (%)	DFS (month)	Chi-square value	value	OS (month)	Chi-square value	value
Gender			3.383	0.066		3.451	0.063
Male	26 (47.27)	101.7 ± 10.91			122.5 ± 11.10
Female	29 (52.73)	137.4 ± 9.292			147.3 ± 7.249
Age			0.584	0.445		0.047	0.829
≥60	15 (27.27)	132.2 ± 12.26			130.3 ± 12.91
<60	40 (72.73)	120.8 ± 9.744			138.3 ± 7.716
Symptoms			0.01	0.921		0.35	0.554
Asymptomatic	6 (10.91)
Abdominal pain/distention	17 (30.91)
Hemorrhage/anemia	31 (56.36)
Abdominal mass	1 (1.82)
Surgical method			2.16	0.142		1.308	0.253
Whipple/child	18 (32.73)	63.30 ± 6.771			73.58 ± 4.941
Local resection	37 (67.27)	131.6 ± 8.522			140.0 ± 6.8
Growth pattern			2.637	0.268		0.62	0.733
Exophytic growth	37 (67.3)	121.7 ± 7.185			123.2 ± 8.342
Intraluminal growth	10 (18.2)	94.14 ± 19.40			144.0 ± 8.981
Both	8 (14.5)	116.8 ± 21.05			117.8 ± 20.39
Tumor size			4.281	0.039		4.867	0.027
≤5 cm	17 (30.91)	135.1 ± 8.105			144.4 ± 6.695
>5 cm	38 (69.09)	101.9 ± 15.67			112.7 ± 16.32
Tumor size			0.003	0.958		0.039	0.844
≤2 cm	9 (16.36)	121.8 ± 14.76			132.7 ± 4.355
2~5 cm	29 (52.73)	135.4 ± 8.946			146.1 ± 8.200
Site			2.548	0.467		2.496	0.476
Bulb	6 (10.91)
Descending	27 (49.09)
Horizontal	21 (38.18)
Ascending	1 (1.818)
Mitotic activity			14.25	0.001		10.05	0.007
<5/50 HPF	40 (72.73)	123.3 ± 9.080			144.4 ± 6.695
5~10/50 HPF	9 (16.36)	103.4 ± 17.88			121.5 ± 18.29
>10/50 HPF	6 (10.91)	40.29 ± 6.047			59.60 ± 10.65
Ki-67 index			26.21	<0.001		12.92	<0.001
≤5%	38 (69.09)	147.3 ± 5.136			151.5 ± 3.492
>5%	17 (30.91)	43.88 ± 6.000			92.53 ± 12.63
Pathological risk			25.28	0.005		11	0.012
Very low	9 (16.36)
Low	24 (43.64)
Intermediate	9 (16.36)
High	13 (23.64)
Imatinib after surgery for middle-high pathological risk			0.478	0.489		0.062	0.804
Yes	6 (27.27)	41.17 ± 7.531			58.00 ± 11.43
No	16 (72.73)	111.3 ± 14.79			122.7 ± 14.55
Imatinib after recurrence						9.811	0.002
Yes	6 (54.55)				125.6 ± 12.16
No	5 (45.45)				35.73 ± 12.71