Diagnosis of Superficial Gastric Lesions Together with Six Gastric Lymphoma Cases via Probe-Based Confocal Laser Endomicroscopy: A Retrospective Observational Study

Table 2

Sensitivity, specificity, PPV, NPV, and diagnostic accuracy of pCLE for gastric lesions ().

	Inflammation or benign ulcer ()	Atrophy and/or IM ()	IEN ()	Adenocarcinoma; ()	Lymphoma; ()	Total (2)
Sensitivity (%); (95% CI)	40.9 (31.6–50.7%)	86.8 (80.4–91.8%)	96.3 (81.0–99.9%)	88.9 (70.8–97.7%)	100 (54.1–100%)	72.4 (67.1–77.2%)
Specificity (%); (95% CI)	94.8 (2.6–9.1%)	81.8 (12.7–24.9%)	87.1 (9.3–17.3%)	97.0 (1.4–5.7%)	100 (98.8–100%)	93.1 (5.6–8.4%)
PPV (%); (95% CI)	80.4 (67.6–89.8%)	81.0 (74.1–86.7%)	40.6 (28.5–53.6%)	72.7 (54.5–86.7%)	100 (54.1–100%)	72.4 (67.1–77.2%)
NPV (%); (95% CI)	75.6 (19.4–30.1%)	87.4 (7.9–18.8%)	99.6 (0.1–2.1%)	99.0 (0.2–3%)	100 (98.8–100%)	93.1 (5.6–8.4%)
Accuracy (%); (95% CI)	76.4 (71.4–80.9%)	84.2 (79.7–88.0%)	87.9 (83.9–91.2%)	96.3 (94.0–98.1%)	100 (98.9–100%)	88.9 (87.3–90.4%)

CI: confidential interval; PPV: positive predictive value; NPV: negative predictive value; IM: intestinal metaplasia; IEN: intraepithelial neoplasia.