Analysis of Prognostic Factors for Resected Synchronous and Metachronous Liver Metastases from Colorectal Cancer

Table 6

Multivariate analysis of factors associated with overall survival.

	value	HR	HR and 95% CI
Timing of metastases presentation/treatment	0.053
Synchronous “combined surgery”	ref	ref	ref
Synchronous “bowel first” surgery”	0.025	2.8	1.1–7
Metachronous	0.895	1.1	0.5–2.3
Positive nodes	0.008
0	ref	ref	ref
1–3	0.267	1.7	0.7–4.4
4+	0.003	3.8	1.6–9.1
Peritoneal resection	0.0003
No	ref	ref	ref
Yes	0.0003	12.1	3.1–46.7
Technique for colon resection	0.007
Open	ref	ref	ref
Minimally invasive	0.007	0.3	0.1–0.7

ref = reference.