Research Article
The Diagnostic and Prognostic Values of C-Reactive Protein and Procalcitonin during Bacterial Infections in Decompensated Cirrhosis
Table 2
Clinical and laboratory variables associated with infection on admission.
| | Bacterial infection group
| Nonbacterial infection group
| value |
| Age (yr) | | | 0.509 | Male/female | 30/30 | 15/17 | 0.775 | Medical history | | | | Diabetes mellitus | 38% | 44% | 0.614 | Hypertension | 28% | 41% | 0.231 | Tabagism | 28% | 19% | 0.350 | Alcoholism | 15% | 13% | 0.786 | Child-Pugh (class) | | | | A | 1% | 6% | 0.123 | B | 28% | 44% | 0.256 | C | 70% | 50% | 0.456 | MELD score | | | <.001 | APACHE II score | | | 0.855 | CLIF-SOFA score | | | 0.757 | ACLF | | | | Grade 1 | 32% | 38% | 0.573 | Grade 2 | 33% | 28% | 0.609 | Grade 3 | 34% | 34% | 0.952 | Duration of stay (d) | | | 0.766 | 3-month mortality | 34% | 3% | 0.008 | Vital signs | | | | Body temperature (°C) | | | 0.008 | Heart rate (beats/min) | | | 0.025 | Respiratory rate (breaths/min) | | | 0.189 | Systolic blood pressure (mm Hg) | | | 0.393 | Diastolic blood pressure (mm Hg) | | | 0.193 | Encephalopathy | 72% | 37% | 0.005 | Ascite | 85% | 84% | 0.647 | WBCs (cells/lL) | | | 0.002 | Neutrophil (cells/lL) | | | 0.001 | Platelet (cells/lL) | | | 0.361 | Serum BUN (mmol/L) | | | 0.282 | Serum creatinine (μmol/L) | | | 0.167 | AST (IU/L) | | | 0.350 | ALT (IU/L) | | | 0.803 | Total bilirubin (mg/L) | | | 0.021 | PT (%) | | | 0.007 | INR | | | 0.005 | Albumin (g/L) | | | 0.579 | Serum sodium | | | 0.177 | CRP (mg/L) | | | <.001 | PCT (ng/mL) | | | <.001 |
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ALT: alanine aminotransferase; AST: aspartate aminotransferase; CRP: C-reactive protein; PCT: procalcitonin; INR: international normalized ratio; WBC: white blood cell; PT: prothrombin time; MELD: Model for End-Stage Liver Disease; APACHE II: Acute Physiology and Chronic Health Disease Classification System II; BUR: blood urea nitrogen; CLIF-SOFA: chronic liver failure-sequential organ failure assessment; ACLF: Acute-on-chronic liver failure.
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