Long-Pulse Gastric Electrical Stimulation Repairs Interstitial Cells of Cajal and Smooth Muscle Cells in the Gastric Antrum of Diabetic Rats

Figure 6

Ultrastructural changes of SMC in the gastric antrum of different groups. In the control group, SMC was spindle shaped with elongated oval nucleus, nuclear uniformed heterochromatin distribution, lots of cytoplasmic dense patches and a dense body, clearly visible filament, and affluent mitochondria. In the DM group, SMC was arranged in disorder with irregular nucleus, massive dark staining chromatin, lots of cytoplasm lysis vacuoles distributed intracellularly, decreased dense bodies and myofilament, swollen mitochondria, vacuolar degeneration, and dissolution. In the DM + GES group, SMC was arranged in neat rows, in fusiform, nuclear heterochromatin distributed evenly, without larger cytoplasmic vacuoles, dense bodies and myofilament rich, and organelles without obvious swelling and expansion. Scale bars are as indicated in each panel.

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