Table of Contents Author Guidelines Submit a Manuscript
Gastroenterology Research and Practice
Volume 2018, Article ID 6961783, 9 pages
https://doi.org/10.1155/2018/6961783
Research Article

Altered Intestinal Microbiota with Increased Abundance of Prevotella Is Associated with High Risk of Diarrhea-Predominant Irritable Bowel Syndrome

1Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
2Institute of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang, China
3Division of Gastroenterology, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA

Correspondence should be addressed to Shujie Chen; nc.ude.ujz@77eijuhsnehc

Received 19 March 2018; Accepted 10 May 2018; Published 5 June 2018

Academic Editor: Aldona Dlugosz

Copyright © 2018 Tingting Su et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. E. Lacy, F. Mearin, L. Chang et al., “Bowel Disorders,” Gastroenterology, vol. 150, no. 6, pp. 1393–1407.e5, 2016. View at Publisher · View at Google Scholar · View at Scopus
  2. R. M. Lovell and A. C. Ford, “Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis,” Clinical Gastroenterology and Hepatology, vol. 10, no. 7, pp. 712–721.e4, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Halland and Y. A. Saito, “Irritable bowel syndrome: new and emerging treatments,” BMJ, vol. 350, article h1622, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. R. E. Ley, M. Hamady, C. Lozupone et al., “Evolution of mammals and their gut microbes,” Science, vol. 320, no. 5883, pp. 1647–1651, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. P. Enck, Q. Aziz, G. Barbara et al., “Irritable bowel syndrome,” Nature Reviews Disease Primers, vol. 2, article 16014, 2016. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Simrén, G. Barbara, H. J. Flint et al., “Intestinal microbiota in functional bowel disorders: a Rome foundation report,” Gut, vol. 62, no. 1, pp. 159–176, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Salonen, W. M. de Vos, and A. Palva, “Gastrointestinal microbiota in irritable bowel syndrome: present state and perspectives,” Microbiology, vol. 156, no. 11, pp. 3205–3215, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. I. B. Jeffery, P. W. O'Toole, L. Öhman et al., “An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota,” Gut, vol. 61, no. 7, pp. 997–1006, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Rajilić–Stojanović, E. Biagi, H. G. H. J. Heilig et al., “Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome,” Gastroenterology, vol. 141, no. 5, pp. 1792–1801, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. L. Krogius-Kurikka, A. Lyra, E. Malinen et al., “Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers,” BMC Gastroenterology, vol. 9, no. 1, p. 95, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Rajilic-Stojanovic, D. M. Jonkers, A. Salonen et al., “Intestinal microbiota and diet in IBS: causes, consequences, or epiphenomena?” The American Journal of Gastroenterology, vol. 110, no. 2, pp. 278–287, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. A. P. M. Kerckhoffs, M. Samsom, M. E. v. d. Rest et al., “Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients,” World Journal of Gastroenterology, vol. 15, no. 23, pp. 2887–2892, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. E. Malinen, T. Rinttila, K. Kajander et al., “Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR,” The American Journal of Gastroenterology, vol. 100, no. 2, pp. 373–382, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. L. Crouzet, E. Gaultier, C. Del'Homme et al., “The hypersensitivity to colonic distension of IBS patients can be transferred to rats through their fecal microbiota,” Neurogastroenterology and Motility, vol. 25, no. 4, pp. e272–e282, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Yatsunenko, F. E. Rey, M. J. Manary et al., “Human gut microbiome viewed across age and geography,” Nature, vol. 486, no. 7402, pp. 222–227, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. G. D. Wu, J. Chen, C. Hoffmann et al., “Linking long-term dietary patterns with gut microbial enterotypes,” Science, vol. 334, no. 6052, pp. 105–108, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Arumugam, J. Raes, E. Pelletier et al., “Enterotypes of the human gut microbiome,” Nature, vol. 473, no. 7346, pp. 174–180, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. The Human Microbiome Project Consortium, “Structure, function and diversity of the healthy human microbiome,” Nature, vol. 486, no. 7402, pp. 207–214, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Cui and Y. Hu, “Multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study,” International Journal of Clinical and Experimental Medicine, vol. 5, no. 3, pp. 238–244, 2012. View at Google Scholar
  20. J. Wheatcroft, D. Wakelin, A. Smith, C. R. Mahoney, G. Mawe, and R. Spiller, “Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction,” Neurogastroenterology and Motility, vol. 17, no. 6, pp. 863–870, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. E. D. Al–Chaer, M. Kawasaki, and P. J. Pasricha, “A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development,” Gastroenterology, vol. 119, no. 5, pp. 1276–1285, 2000. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Sivan, L. Corrales, N. Hubert et al., “Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy,” Science, vol. 350, no. 6264, pp. 1084–1089, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. S. M. Man, Q. Zhu, L. Zhu et al., “Critical role for the DNA sensor AIM2 in stem cell proliferation and cancer,” Cell, vol. 162, no. 1, pp. 45–58, 2015. View at Publisher · View at Google Scholar · View at Scopus
  24. J. Tap, M. Derrien, H. Törnblom et al., “Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome,” Gastroenterology, vol. 152, no. 1, pp. 111–123.e8, 2017, e118. View at Publisher · View at Google Scholar · View at Scopus
  25. Y. Liu, L. Zhang, X. Wang et al., “Similar fecal microbiota signatures in patients with diarrhea-predominant irritable bowel syndrome and patients with depression,” Clinical Gastroenterology and Hepatology, vol. 14, no. 11, pp. 1602–1611.e5, 2016, e1605. View at Publisher · View at Google Scholar · View at Scopus
  26. L. Rigsbee, R. Agans, V. Shankar et al., “Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrome,” The American Journal of Gastroenterology, vol. 107, no. 11, pp. 1740–1751, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. H.-Y. Qin, J. C. Y. Wu, X.-D. Tong, J. J. Y. Sung, H.-X. Xu, and Z.-X. Bian, “Systematic review of animal models of post-infectious/post-inflammatory irritable bowel syndrome,” Journal of Gastroenterology, vol. 46, no. 2, pp. 164–174, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Bercik, L. Wang, E. F. Verdu et al., “Visceral hyperalgesia and intestinal dysmotility in a mouse model of postinfective gut dysfunction,” Gastroenterology, vol. 127, no. 1, pp. 179–187, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. C. Keating, M. Beyak, S. Foley et al., “Afferent hypersensitivity in a mouse model of post-inflammatory gut dysfunction: role of altered serotonin metabolism,” The Journal of Physiology, vol. 586, no. 18, pp. 4517–4530, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. D. Dodd, R. I. Mackie, and I. K. O. Cann, “Xylan degradation, a metabolic property shared by rumen and human colonic Bacteroidetes,” Molecular Microbiology, vol. 79, no. 2, pp. 292–304, 2011. View at Publisher · View at Google Scholar · View at Scopus
  31. P. Kovatcheva-Datchary, A. Nilsson, R. Akrami et al., “Dietary fiber-induced improvement in glucose metabolism is associated with increased abundance of Prevotella,” Cell Metabolism, vol. 22, no. 6, pp. 971–982, 2015. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Bourdu, M. Dapoigny, E. Chapuy et al., “Rectal instillation of butyrate provides a novel clinically relevant model of noninflammatory colonic hypersensitivity in rats,” Gastroenterology, vol. 128, no. 7, pp. 1996–2008, 2005. View at Publisher · View at Google Scholar · View at Scopus
  33. H. M. Staudacher, P. M. Irving, M. C. E. Lomer, and K. Whelan, “Mechanisms and efficacy of dietary FODMAP restriction in IBS,” Nature Reviews. Gastroenterology & Hepatology, vol. 11, no. 4, pp. 256–266, 2014. View at Publisher · View at Google Scholar · View at Scopus
  34. J. U. Scher, A. Sczesnak, R. S. Longman et al., “Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis,” eLife, vol. 2, article e01202, 2013. View at Google Scholar
  35. S. M. Dillon, E. J. Lee, C. V. Kotter et al., “Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection,” Mucosal Immunology, vol. 9, no. 1, pp. 24–37, 2016. View at Publisher · View at Google Scholar · View at Scopus
  36. J. R. Lukens, P. Gurung, P. Vogel et al., “Dietary modulation of the microbiome affects autoinflammatory disease,” Nature, vol. 516, no. 7530, pp. 246–249, 2014. View at Publisher · View at Google Scholar · View at Scopus
  37. P. Mangell, P. Nejdfors, M. Wang et al., “Lactobacillus plantarum 299v inhibits Escherichia coli-induced intestinal permeability,” Digestive Diseases and Sciences, vol. 47, no. 3, pp. 511–516, 2002. View at Publisher · View at Google Scholar · View at Scopus
  38. L. A. David, C. F. Maurice, R. N. Carmody et al., “Diet rapidly and reproducibly alters the human gut microbiome,” Nature, vol. 505, no. 7484, pp. 559–563, 2014. View at Publisher · View at Google Scholar · View at Scopus