Mean Corpuscular Volume as a Predictive Factor of Response to Preoperative Chemoradiotherapy in Locally Advanced Rectal Cancer

Table 1

Patient characteristics.

Variable	Response (26)	No response (29)
Sex
Female	5	4	0.721
Male	21	25
Age (y)
Median (range)	60 (38–88)	57 (31–87)	0.145
Differentiation
Low	14	3	<0.001
Moderate	10	12
High	2	14
White blood cell count (×10^9)
Median (range)	6.20 (3.89–12.50)	6.46 (3.27–12.44)	0.416
Neutrophil granulocyte (×10^9)
Median (range)	3.62 (2.36–10.20)	4.20 (1.79–10.70)	0.434
Monocyte (×10^9)
Median (range)	0.50 (0.26–0.90)	0.59 (0.15–1.07)	0.142
Lymphocyte (×10^9)
Median (range)	1.91 (0.80–3.90)	1.40 (0.80–3.02)	0.017
Eosinophilic granulocyte (×10^9)
Median (range)	0.11 (0–0.50)	0.14 (0–0.44)	0.195
Basophilic granulocyte (×10^9)
Median (range)	0.015 (0–0.10)	0 (0–0.04)	0.050
Neutrophil-to-lymphocyte ratio (NLR)
Median (range)	2.08 (1.02–12.75)	2.91 (0.99–11.89)	0.085
Lymphocyte-to-monocyte ratio (LMR)
Median (range)	3.69 (1.00–9.75)	2.40 (1.05–6.49)	0.024
Neutrophil-to-monocyte ratio (NMR)
Median (range)	7.24 (3.27–20.35)	8.01 (2.27–26.50)	0.837
Hemoglobin (g/l)
Median (range)	133.50 (83.00–158.00)	137.00 (96.00–168.00)	0.294
Hematocrit (HCT) (l/l)
Median (range)	0.40 (0.26–0.46)	0.39 (0.30–0.50)	0.329
Mean corpuscular volume (MCV) (fl)
Median (range)	92.20 (77.70–98.00)	85.90 (63.30–96.10)	<0.001
Red cell distribution width (RDW) (%)
Median (range)	12.95 (11.80–20.80)	13.10 (11.80–18.00)	0.712
Platelet (×10^9)
Median (range)	212.50 (123.00–656.00)	235.00 (116.00–501.00)	0.554
Platelet-to-lymphocyte ratio (PLR)
Median (range)	115.71 (51.25–381.25)	136.40 (74.09–357.89)	0.006
Thrombocytocrit (g/l)
Median (range)	0.21 (0.12–0.42)	0.24 (0.15–0.50)	0.303
CEA (ng/ml)
Median (range)	2.85 (0.30–9.50)	4.90 (0.60–27.70)	0.002
AFP (ng/ml)
Median (range)	2.53 (1.36–11.90)	2.70 (1.60–10.53)	0.727
CA199 (ng/ml)
Median (range)	12.50 (0.80–2153.70)	7.60 (0.80–4269.70)	0.864