Research Article

Association of Total Fluid Intake and Output with Duration of Hospital Stay in Patients with Acute Pancreatitis

Table 3

Associations between baseline patient characteristics and length of hospital stay.

VariableMultiplicative effect on mean LOS (95% CI) value

Age at hospital admission (10-year increase)1.00 (0.98, 1.01)0.61
Sex (female)1.29 (0.79, 2.11)0.30
Primary etiologyTest of overall difference:
 ETOH1.00 (reference)N/A
 Biliary0.95 (0.52, 1.73)0.88
 Other2.07 (1.17, 3.66)0.012
Any antihypertensive medication at the time of hospital admission0.85 (0.49, 1.48)0.57
BMI (5-unit increase)1.17 (0.93, 1.47)0.17
Heart rate (10-unit increase)1.19 (1.08, 1.32)0.0005
Respiratory rate (10-unit increase)1.91 (1.36, 2.69)0.0002
Systolic blood pressure (10-unit increase)0.86 (0.79, 0.92)<0.0001
Diastolic blood pressure (10-unit increase)0.86 (0.76, 0.96)0.0102
Oxygen saturation (5-unit increase)0.98 (0.66, 1.44)0.92
BISAP scoreTest of overall difference:
 01.00 (reference)N/A
 11.42 (0.77, 2.61)0.26
 2–43.11 (1.83, 5.30)<0.0001
Hematocrit (10-unit increase)0.53 (0.37, 0.76)0.0005
Hemoglobin (1-unit increase)0.87 (0.79, 0.95)0.0028
Sodium (5-unit increase)0.69 (0.54, 0.88)0.0032
Potassium (1-unit increase)1.13 (0.89, 1.43)0.32
Calcium (1-unit increase)0.77 (0.65, 0.92)0.0040
Bicarbonate (5-unit increase)0.55 (0.42, 0.72)<0.0001
Creatinine (doubling)1.73 (1.36, 2.19)<0.0001
BUN (doubling)1.76 (1.41, 2.21)<0.0001
Triglycerides (doubling)1.25 (1.04, 1.49)0.0177

LOS = length of stay; CI = confidence interval. Multiplicative effects, 95% CIs, and values result from single-variable (i.e., unadjusted) negative binomial regression models.