The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss

Table 2

Summary of RCTs on the EndoBarrier.

Study	Number of patients	BMI	Implant duration (weeks)	Weight loss	Change in HBA1c	Stent removal rate
Gersin et al. [6]	47; 21 in treatment arm	46 kg/m^2	12	−8.2 kg ± 1.3 kg in treatment arm versus 2 kg ± 1.1 kg in sham arm	Not an endpoint	38%
Koehestanie et al. [4]	73; 34 in treatment arm	35 kg/m^2 device; 37 kg/m^2 in control	26	10.6 kg device; 5.3 kg in control	−1.3% versus 0.4% in control	3%
Rodriguez-Grunert et al. [7]	18; 12 in treatment arm	39 kg/m^2	24	−10.2 kg ± 1.3 kg in device arm versus 7.1 ± 4.3 kg in sham arm	−2.4 ± 0.7% versus −0.8 ± 0.4% in control	25%
Schouten et al. [5]	41; 30 in treatment arm	49 kg/m^2	12	19% in device; 6.9% in control	−1.1% versus 0.4% in control	15%
Tarnoff et al. [8]	35; 29 in treatment arm	42 kg/m^2 in device; 40 kg/m^2 in control	12	−10.3 kg ± 3.2 kg versus 2.6 kg ± 3.5 kg in the control group	Not an endpoint	20%