Review Article
Perioperative Care of Patients with Inflammatory Bowel Disease: Focus on Nutritional Support
Table 1
Predictors of aggressive Crohn’s disease [
4–
7].
| (i) Clinical risk factors | (a) Young age at presentation | (b) Steroids required at first presentation or within 6 months | (c) Perianal disease | (d) Upper tract disease | (e) >2 steroid courses | (f) Current smokers | (g) Multiple admissions | (h) Early resection | (ii) Increased number of positive antibodies identified children at risk for complicated disease | (a) ANCA, ASCA, and anti-CBir 1 | (iii) One or more NOD2 mutations associated with aggressive fibrostenotic course | (iv) Presence of a stricture on CTE, MRE, or colonoscopy risk factor for future complications (fistula, abscess, perforation, and obstruction) |
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ANCA: antineutrophil cytoplasmic antibodies; ASCA: anti-Saccharomyces cerevisiae antibodies; anti-CBir 1: bacterial flagellin antibodies; NOD2: nucleotide-binding oligomerization domain-containing protein 2; CTE: computed tomography enterography; MRE: magnetic resonance enterography.
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