White Blood Cell and Granulocyte Counts Are Independent Predictive Factors for Prognosis of Advanced Pancreatic Caner

Table 3

Univariate analyses examining the association between clinical characteristics and survival in pancreatic cancer patients.

Characteristics	(%)	HR	95% CI	value
Gender
Female	77 (36.0%)	1	Reference
Male	137 (64.0%)	1.121	0.800–1.570	0.508
Age
≤60	101 (47.2%)	1	Reference
>60	113 (52.8%)	0.950	0.691–1.305	0.750
Locations
Head	81 (37.9%)	1	Reference
Body/tail	133 (62.1%)	1.352	0.965–1.893	0.080
TNM classification
Stage 3	83 (38.8%)	1	Reference
Stage 4	131 (61.2%)	0.892	0.314–1.755	0.494
Baseline WBC
<5.8 × 10^9/L	107 (50%)	1	Reference
≥5.8 × 10^9/L	107 (50%)	2.132	1.524–2.976	<0.0001
Baseline granulocyte
<3.7 × 10^9/L	106 (49.5%)	1	Reference
≥3.7 × 10^9/L	108 (50.5%)	2.849	2.016–4.016	<0.0001
Baseline neutrophil
<3.9 × 10^9/L	104 (48.6%)	1	Reference
≥3.9 × 10^9/L	110 (51.4%)	2.488	1.770–3.497	<0.0001
Baseline lymphocyte
<1.4 × 10^9/L	123 (57.5%)	1	Reference
≥1.4 × 10^9/L	91 (42.5%)	0.710	0.516–0.974	0.034
Baseline NLR
<2.8	105 (49.1%)	1	Reference
≥2.8	109 (50.9%)	2.183	1.567–3.040	<0.0001
Baseline PLR
<124.6	107 (50%)	1	Reference
≥124.6	107 (50%)	1.241	0.904–1.704	0.182

HR: hazard ratio; CI: confidence interval; WBC: white blood cell; NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio.