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Gastroenterology Research and Practice
Volume 2018, Article ID 8454125, 8 pages
Research Article

Epidemiological and Clinical-Pathological Aspects of Helicobacter pylori Infection in Brazilian Children and Adults

1UNESP-São Paulo State University, Department of Biology, São José do Rio Preto, SP, Brazil
2UFMS-Federal University of Mato Grosso do Sul, School of Medicine, MS, Brazil
3João Paulo II Hospital, Service of Endoscopy, São José do Rio Preto, SP, Brazil

Correspondence should be addressed to Ana Elizabete Silva; rb.psenu.eclibi@etebana

Received 23 January 2018; Accepted 10 June 2018; Published 4 September 2018

Academic Editor: Haruhiko Sugimura

Copyright © 2018 Evelyn Pedroso Toscano et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. To evaluate the prevalence and risk factors of H. pylori infection in the pediatric and adult population seen at a public hospital in São José do Rio Preto, SP, Brazil. Methods. This is a retrospective study that evaluated 2406 medical records of children, adolescents, and adults with dyspeptic symptoms who underwent upper gastrointestinal endoscopy. H. pylori diagnosis and demographic and clinical-pathological features were recorded. Results. A total of 852 subjects were H. pylori positive, with an overall prevalence of infection of 35.4%, occurring mainly in adults over 40 years of age, and a 24.7% prevalence considering only children and adolescents. No association was observed between H. pylori infection and risk factors. However, the H. pylori positive individuals showed a higher frequency of pangastritis (), severe lesions (), and erosive lesions (). The bacterium was eradicated in 83.5% (127) of the patients who received the standard therapy. Conclusions. The prevalence of H. pylori detected in a public service in São José do Rio Preto, SP, Brazil, is as expected for developed countries, showing growing rates with increasing age. As H. pylori infection occurs during childhood, screening programs for detection and prevention in the pediatric population are important to reduce the prevalence of this infection in adults.