Diagnostic Value of CA 19-9 and Carcinoembryonic Antigen for Pancreatic Cancer: A Meta-Analysis

Table 1

Characteristics of the studies included in the meta-analysis.

Author	Year	Country		Mean age	Male/female	Gold standard	Cases of pancreatic cancer	Cutoff value of CA 19-9	Cutoff value of CEA
Benini	1988	Italy	193	53.1	117/76	Histology	25	37 U/ml	8.4 ng/ml
Satake	1994	Japan	2522	NA	NA	Pathological	641	37 U/ml	2.5 ng/ml
Louhimo	2002	Finland	320	59.9	189/131	Histology	33	35 U/ml	5 ng/ml
Carpelan-Holmstrom	2002	Finland	286	NA	NA	Histology	30	35 U/ml	5 ng/ml
Ozkan	2003	Turkey	135	57.3	NA	Histopathologic	40	37 U/ml	5 ng/ml
Nazli	2000	Turkey	100	57.1	49/51	Histopathologic	40	37 U/ml	5 ng/ml
Maire	2008	France	41	64.0	14/27	Pathological	10	37 U/ml	5 ng/ml
Gu	2015	China	132	56.5	68/64	Pathological	52	37 U/ml	5 ng/ml
Jiang	2004	China	312	NA	NA	Pathological	129	37 U/ml	5 ng/ml
Duraker	2007	Turkey	181	NA	NA	Histology	123	37 U/ml	5 ng/ml
Fritz	2011	Germany	142	31–87	82/60	Histology	50	37 U/ml	2.5 or 5 ng/ml
Ferri	2016	Spain	82	61.6	48/34	Histopathologic	47	37 U/ml	5 ng/ml
Pezzilli	2016	Italy	91	61.6	54/37	Histology	56	37 U/ml	3 ng/ml