The Therapeutic Effect of a Multistrain Probiotic on Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study

Table 3

Results of lactulose hydrogen breath test and fecal calprotectin before and after probiotic ingestion.

(a) Lactulose hydrogen breath test

Positive subjects at baseline (%)	Positive subjects at 8th week (%)
6 (54.5)	4 (40)

(b) Fecal calprotectin

	Mean value at baseline (mg/kg)	Mean value at 8th week (mg/kg)	value
FAS group	323.4 ± 684.9	180.4 ± 327.1	0.375
PPS group	364.4 ± 729.1	200.9 ± 347.6	0.375

Comparisons of the fecal calprotectin value before and after consumption of probiotics were analyzed using the Wilcoxon signed-rank test. FAS: full analysis set; PPS: per protocol set.