The Role of C-Reactive Protein in the Early Prediction of Serious Pancreatic Fistula Development after Pancreaticoduodenectomy

Table 7

ROC analysis with maximum combination of sensitivity and specificity of CRP values and their changes to predict clinically relevant POPF.

Parameter	Value		AUC	Sensitivity	Specificity	95% CI
						Lower bound	Upper bound
POD1 CRP	>5.5	0.335	0.407	70	27.1	0.226	0.588
POD3 CRP	>22.5	0.080	0.668	70	71	0.508	0.828
POD5 CRP	>19	0.0001	0.851	90	82.2	0.742	0.959
Δ POD3-POD1	>7.5	0.042	0.695	80	58.9	0.546	0.844
Δ POD5-POD1	>2.5	0.0001	0.853	100	63.6	0.770	0.937
Δ POD5-POD3	> −7.5	0.045	0.692	90	42.1	0.527	0.857