Review Article

How the BRAF V600E Mutation Defines a Distinct Subgroup of Colorectal Cancer: Molecular and Clinical Implications

Figure 2

Diagram of the serrated and conventional pathways of colorectal cancer. Bold text indicates the pathways leading to BRAF mutant cancers. ACF: aberrant crypt foci; GCHP: goblet cell hyperplastic polyp; MVHP: microvesicular hyperplastic polyp; SSA: sessile serrated adenoma; TSA: traditional serrated adenoma; TA: tubular adenoma; TVA: tubulovillous adenoma.