What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research

Table 2

Summary of clinical trials using a single strain of probiotics with antibiotics.

Author	Study size	Probiotic	Study type	Result
Zhao et al. [44]	240	Saccharomyces boulardii	A prospective, randomized, controlled study	Eradication rate; Probiotic: 85.0%; No probiotic: 75.8%; Adverse reaction decreases
Dore et al. [45]	45	Lactobacillus reuteri (DSM 17938)	A case report series	Eradication rate: 93.3%
Cekin et al. [18]	159	Bifidobacterium animalis subsp. lactis B94	Randomized, placebo-controlled study	Eradication rate; Probiotic: 86.8%; No probiotics: 70.8%; Adverse reaction decreases
Zhu et al. [46]	240	Saccharomyces boulardii	Randomized clinical trial	Saccharomyces boulardii reduced the overall side effect rate, and there was no difference observed in efficacy on the eradication rate
Chen et al. [47]	105	Clostridium butyricum	Open-label, randomized clinical trial	No significant difference in eradication rates was observed. Supplementation of probiotics led to improvement of gastrointestinal symptoms