Diclofenac Sodium Treatment Ameliorates Extrapancreatic Organ Injuries in a Murine Model of Acute Pancreatitis Induced by Caerulein

Table 2

Histopathological results obtained from the lung tissue according to groups.

	Group 1 ()	Group 2 ()	Group 3 ()	Group 4 ()	Group 5 ()	Group 6 ()	Group 7 ()	value^†
Congestion	0 (0–0.25)	2 (2–2)^a	1 (0–1.25)^b	1 (1–2)^a,b	2 (1–2)^a,c	1 (1–1)^a,b,d	1 (1–2)^a,b	<0.001
Edema	0 (0–1)	1 (1–1)^a	0 (0–1)^b	0 (0–1)^b	1 (0–1)	0 (0–0)^b,d	1 (1–1)^a,c,e,f	<0.001
Neutrophil infiltration	0 (0–0)	0 (0–1)	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)^b	<0.001
Mononuclear infiltration	0 (0–0)	0 (0–1.5)	0 (0–0)	0 (0–0)	0 (0–0.5)	0 (0–0)^b	0 (0–0)	0.030
Alveolary wall thickness	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)	>0.999
Emphysematous changes	0 (0–1)	1 (1–1)^a	0 (0–0)^b	1 (0.75–1)^c	1 (1–1)^a,c	1 (1–1)^a,c	1 (1–1)^a,c	<0.001

Data were shown as median (25th–75th) percentiles, the Kruskal–Wallis test. ^aThe difference between the considered group and group 1 was found as statistically significant (). ^bThe difference between the considered group and group 2 was found as statistically significant (). ^cThe difference between the considered group and group 3 was found as statistically significant (). ^dThe difference between the considered group and group 5 was found as statistically significant (). ^eThe difference between the considered group and group 4 was found as statistically significant (). ^fThe difference between the considered group and group 6 was found as statistically significant ().