Artificial Neural Network Individualised Prediction of Time to Colorectal Cancer Surgery

Table 1

Patient and tumour demographics. The entire cohort was dichotomised using each studied timepoint. As expected, a number of significant differences are observed.

Time from diagnosis to curative laparoscopic surgery; ()	Whole cohort; 668 (100%)	4 weeks or less; 296 (44.3%)	Greater than 4 weeks; 372 (55.7%)		8 weeks or less; 537 (80.4%)	Greater than 8 weeks; 131 (19.6%)		12 weeks or less; 578 (86.5%)	Greater than 12 weeks; 90 (13.5%)
Age (mean)	70	71	70	0.339	71	69	0.009	67	71	0.001
Males ()	389 (58.2%)	169 (57.1%)	220 (59.1%)	0.594	300 (55.9%)	89 (67.9%)	0.012	325 (56.2%)	64 (71%)	0.008
Body mass index (median)	26	26	26	0.601	26	26	0.565	26	26	0.444
ASA ()
1	79 (11.8%)	47 (15.9%)	32 (8.6%)	0.07	72 (13.4%)	7 (5.3%)	0.008	74 (12.8%)	5 (5.6%)	0.167
2	420 (62.9%)	176 (59.5%)	244 (65.6%)		340 (63.3%)	80 (61.1%)		365 (63.1%)	55 (61.1%)
3	161 (24.1%)	68 (23%)	93 (25%)		118 (22%)	43 (32.8%)		131 (22.3%)	30 (33.3%)
4	4 (0.6%)	2(0.7%)	2 (0.5%)		3 (0.6%)	1 (0.8%)		3 (0.5%)	0
Unknown	4 (0.6%)	3(1%)	1 (0.3%)		4 (0.7%)	0		5 (0.9%)	0
Tumour location
Colon	407 (60.9%)	217 (73.3%)	190 (51.1%)	<0.001	357 (66.5%)	50 (38.2%)	<0.001	382 (61.1%)	25 (27.8%)	<0.001
Rectum	261 (39.1%)	79 (26.7%)	182 (48.9%)		180 (33.5%)	81 (61.8%)		196 (33.9%)	65 (72.2%)
Tumour stage (TNM 5th edition)
0	42 (6.3%)	16 (5.4%)	26 (7%)	0.249	32 (6%)	10 (7.6%)	0.098	34 (5.9%)	8 (8.9%)	0.109
1	138 (20.7%)	49 (16.6%)	89 (23.9%)		109 (20.3%)	29 (22.1%)		117 (20.2%)	21 (23.3%)
2	220 (32.9%)	115 (38.9%)	105 (28.2%)		189 (35.2%)	31 (23.7%)		200 (34.6%)	20 (22.2%)
3	208 (31.1%)	91 (30.7%)	117 (31.5%)		165 (30.7%)	43 (32.8%)		179 (31%)	29 (32.2%)
4	36 (5.4%)	16 (5.4%)	20 (5.4%)		25 (4.7%)	11 (8.4%)		28 (4.8%)	8 (8.9%)
Unknown	24 (3.6%)	9 (3%)	15 (4%)		17 (3.2%)	7 (5.3%)		20 (3.5%)	4 (4.4%)
Neoadjuvant treatment	57 (8.5%)	4 (1.4%)	53 (14.2%)	<0.001	14 (2.6%)	43 (32.8%)	<0.001	16 (2.8%)	41 (45.6%)	<0.001
Stoma planned	235 (35.1%)	72 (24.3%)	163 (43.8%)	<0.001	155 (28.9%)	80 (61.1%)	<0.001	169 (29.2%)	66 (73.3%)	<0.001