Quantitative Analysis of HER2 Amplification by Droplet Digital PCR in the Follow-Up of Gastric Cancer Patients Being Treated with Trastuzumab after Surgery
Monitoring plasma HER2 ratios during clinical courses of GC patients. Changes in plasma HER2 ratios during the 12 months of the follow-up period. Seven patients (cases 2, 3, 5, 6, 7, 9, and 11) were found to have progressive disease (PD), and four patients (cases 2, 6, 9, and 11) had died. The increases in their plasma HER2 ratios were observed at the time of PD, which was approximately 2.3-4.1 times higher than the cut-off value. The 0 month means presurgery. The horizontal dotted line represents the cut-off value of HER2 ratios ().
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.