Research Article

Quantitative Analysis of HER2 Amplification by Droplet Digital PCR in the Follow-Up of Gastric Cancer Patients Being Treated with Trastuzumab after Surgery

Table 3

Concordance of plasma and tumor tissue sample results for HER2 status from GC patients by ddPCR or IHC/FISH.

HER2 in FFPE with ddPCRTotalSensitivitySpecificity
PositiveNegative

HER2 in FFPE with IHC/FISH
 Positive3453987.2%95.2%
 Negative36063
HER2 in ctDNA with ddPCR
 Positive2683476.5%83.8%
 Negative115768