Mutation Profiling of Premalignant Colorectal Neoplasia

Figure 1

The structure of genetic variance among the investigated samples. Waterfall plot of genes mutated in >5% of samples. Mutation frequency, shown in the top panel, is calculated relative to the assayed DNA length (1.29 Mb). LGD: low-grade dysplasia; HGD: high-grade dysplasia; LGD-H: low-grade dysplasia adjacent to areas of high-grade dysplasia and/or carcinoma; AC: adenocarcinoma.