Research Article
Prognostic Factors Influencing Infectious Complications after Cytoreductive Surgery and HIPEC: Results from a Tertiary Referral Center
Table 4
Correlation between risk factors and infectious complications (univariate analysis).
| Variables | Patients () (%) | Infectious complication () (%) | |
| Age (years) | | | | <61 | 82 (41) | 19 (45) | 0.06 | >61 | 118 (59) | 23 (55) | | ASA score | | | | <3 | 184 (92) | 12 (28) | 0.018 | >3 | 16 (8) | 30 (72) | | SGA score | | | | A | 102 (51) | 11 (26) | 0.016 | B/C | 98 (49) | 31 (74) | | P. status (ECOG) | | | | <2 | 107 (53) | 15 (36) | 0.03 | >2 | 93 (47) | 27 (64) | | Cytoreduction | | | | Primary | 124 (62) | 20 (48) | 0.1 | Secondary | 76 (38) | 22 (52) | | PCI score | | | | <15 | 62 (31) | 16 (38) | 0.05 | >15 | 138 (69) | 26 (62) | | Ascites | | | | Yes | 92 (46) | 23 (55) | 0.06 | No | 108 (54) | 19 (45) | | Prev. chemotherapy | | | | Yes | 104 (52) | 24 (57) | 0.07 | No | 96 (48) | 18 (43) | | Intestinal obstruction | | | | Yes | 42 (21) | 20 (48) | 0.1 | No | 158 (79) | 22 (52) | | Colorectal resections | | | | Yes | 138 (69) | 28 (67) | 0.024 | No | 62 (31) | 14 (33) | | Length of surgical procedure (min) | | | | | | | <423 | 159 (79.5) | 17 (40) | 0.059 | >423 | 41 (20.5) | 25 (60) | | Number of surgical procedures | | | | | | | <4 | 18 (9) | 18 (43) | 0.07 | >4 | 182 (91) | 24 (57) | | Blood loss (ml) | | | | <1400 | 93 (46.5) | 13 (31) | 0.04 | >1400 | 107 (53.5) | 29 (69) | | ICU stay (hours) | | | | <31 | 78 (39) | 17 (40) | 0.059 | >31 | 122 (61) | 25 (60) | | HIPEC drugs | | | | Cisplatin | 132 (66) | 20 (48) | 0.1 | Oxaliplatin | 68 (34) | 22 (52) | | Post-op serum albumin (g/dl) | | | | | | | <2 | 54 (27) | 29 (69) | 0.03 | >2 | 146 (73) | 13 (31) | |
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