Research Article

Prognostic Factors Influencing Infectious Complications after Cytoreductive Surgery and HIPEC: Results from a Tertiary Referral Center

Table 4

Correlation between risk factors and infectious complications (univariate analysis).

VariablesPatients () (%)Infectious complication () (%)

Age (years)
 <6182 (41)19 (45)0.06
 >61118 (59)23 (55)
ASA score
 <3184 (92)12 (28)0.018
 >316 (8)30 (72)
SGA score
 A102 (51)11 (26)0.016
 B/C98 (49)31 (74)
P. status (ECOG)
 <2107 (53)15 (36)0.03
 >293 (47)27 (64)
Cytoreduction
 Primary124 (62)20 (48)0.1
 Secondary76 (38)22 (52)
PCI score
 <1562 (31)16 (38)0.05
 >15138 (69)26 (62)
Ascites
 Yes92 (46)23 (55)0.06
 No108 (54)19 (45)
Prev. chemotherapy
 Yes104 (52)24 (57)0.07
 No96 (48)18 (43)
Intestinal obstruction
 Yes42 (21)20 (48)0.1
 No158 (79)22 (52)
Colorectal resections
 Yes138 (69)28 (67)0.024
 No62 (31)14 (33)
Length of surgical procedure (min)
 <423159 (79.5)17 (40)0.059
 >42341 (20.5)25 (60)
Number of surgical procedures
 <418 (9)18 (43)0.07
 >4182 (91)24 (57)
Blood loss (ml)
 <140093 (46.5)13 (31)0.04
 >1400107 (53.5)29 (69)
ICU stay (hours)
 <3178 (39)17 (40)0.059
 >31122 (61)25 (60)
HIPEC drugs
 Cisplatin132 (66)20 (48)0.1
 Oxaliplatin68 (34)22 (52)
Post-op serum albumin (g/dl)
 <254 (27)29 (69)0.03
 >2146 (73)13 (31)

Significant.