The Clinical and Economic Burden of Colorectal Anastomotic Leaks: Middle-Income Country Perspective

Table 5

GLM for total costs (index admission plus readmissions).

Variable	Crude estimate	95% CI		Multivariable estimate	95% CI
Anastomotic leak	6.13	4.49–8.35	<0.001	4.66	3.48–6.23	<0.001
Emergency surgery	1.81	1.40–2.32	<0.001	1.25	1.01–1.54	0.038
Age	1.02	1.01–1.02	<0.001	1.01	1.01–1.02	<0.001
Male gender	1.47	1.21–1.78	<0.001	0.87	0.74–1.01	0.070
Laparoscopy	0.683	0.56–0.83	<0.001	1.29	1.11–1.52	0.001
Cancer	1.54	1.25–1.90	<0.001	1.29	1.09–1.52	0.002
Protective stoma	3.15	2.50–3.97	<0.001	1.91	1.54–2.36	<0.001
Intercept	—	—	—	14,221	10,739–18,832	<0.001

Multivariable estimates were adjusted for all the variables presented in this table.