Effects of Ethyl Pyruvate on Bile Duct Ligation-Induced Liver Fibrosis by Regulating Nrf2 Pathway and Proinflammatory Cytokines in Rats

Figure 1

EP improved liver function in rats. (a) HE staining (×400). (b) Masson’s trichrome staining at 4 weeks (×100). (c) The serum ALT and AST levels and the semiquantitation of hepatic fibrosis using pathological scoring with Masson’s trichrome staining (: vs. sham group, , ; #: vs. BDL group, ^#, ^##, per group). ; “→” indicates the positions of disordered lobular structure and bile duct epithelial hyperplasia.

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