Gastroenterology Research and Practice / 2019 / Article / Tab 1

Research Article

Unmet Medical Needs in the Management of Ulcerative Colitis: Results of an Italian Delphi Consensus

Table 1

Final statements and voting results.

% consensus

1There is a need for a treatment strategy that can induce sustained corticosteroid-free remission and mucosal healing in the majority of patients95.1
2There is a need for a therapy with rapid onset of action75.6
3There is a need for drugs that are associated with only minimal or no loss of response95.1
4There is a need for therapies that can effectively treat moderate-to-severe disease80.5
5There is an unmet need for individualised treatment based on reliable predictors of response95.1
6There is an unmet need for a therapeutic strategy that can reduce hospitalisation and need for surgery85.4

Monitoring and risk management
7There is an unmet need for validated, noninvasive methods to monitor disease activity75.6
8There is an unmet need for management strategies with better benefit/risk ratio75.6
9There is a need for effective and appropriate strategies that can limit the risk of developing colorectal cancer61.0

Patient-related issues
10There is an unmet need for therapies that are more compatible with patients’ expectations and comorbidities80.5
11There is a need for consensus regarding assessment of quality of life, fatigue, psychological symptoms, social problems, and disability85.4

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