Unmet Medical Needs in the Management of Ulcerative Colitis: Results of an Italian Delphi Consensus

Table 1

Final statements and voting results.

		% consensus
Treatment
1	There is a need for a treatment strategy that can induce sustained corticosteroid-free remission and mucosal healing in the majority of patients	95.1
2	There is a need for a therapy with rapid onset of action	75.6
3	There is a need for drugs that are associated with only minimal or no loss of response	95.1
4	There is a need for therapies that can effectively treat moderate-to-severe disease	80.5
5	There is an unmet need for individualised treatment based on reliable predictors of response	95.1
6	There is an unmet need for a therapeutic strategy that can reduce hospitalisation and need for surgery	85.4
Monitoring and risk management
7	There is an unmet need for validated, noninvasive methods to monitor disease activity	75.6
8	There is an unmet need for management strategies with better benefit/risk ratio	75.6
9	There is a need for effective and appropriate strategies that can limit the risk of developing colorectal cancer	61.0
Patient-related issues
10	There is an unmet need for therapies that are more compatible with patients’ expectations and comorbidities	80.5
11	There is a need for consensus regarding assessment of quality of life, fatigue, psychological symptoms, social problems, and disability	85.4