Fibrinogen and Albumin Score Changes during Preoperative Treatment Can Predict Prognosis in Patients with Locally Advanced Rectal Cancer

Table 2

Association between clinicopathological factors and changes in FA scores.

	FA score decreased or unchanged ()	FA score increased ()
Age (years)			0.017
≤60	47	6
>60	37	16
Sex			0.219
Female	23	9
Male	61	13
Distance from anal verge (cm)			0.436
≤5	46	10
>5	38	12
Pathologic differentiation			0.938
Well, moderately	72	19
Poorly, mucinous	12	3
CEA (ng/ml)			0.872
≤5	55	14
>5	29	8
CA19-9 (ng/ml)			0.112
≤37	70	15
>37	14	7
Pathologic T stage			0.766
T0-2	60	15
T3-4	24	7
Pathologic N stage			0.825
N0	63	17
N+	21	5
LVI			0.073
Negative	74	16
Positive	10	6
PNI			0.730
Negative	70	19
Positive	14	3
pCR			0.303
Yes	20	3
No	64	19
Downstage			0.971
Yes	50	13
No	34	9
Pre-CRT Fib			0.051
Post-CRT Fib			≤0.001
Pre-CRT Alb			0.649
Post-CRT Alb			0.003

pCR: pathologic complete response; CEA: carcinoembryonic antigen; CA19-9: carbohydrate antigen 19-9; CRT: chemoradiotherapy; LVI: lymph vascular invasion; PNI: perineural invasion; Fib: fibrinogen; Alb: albumin; FA: fibrinogen and albumin. Independent -tests were used to analyze with continuous variables.