Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer
FNDCs and GPR116 expression in nonaffected human mucosal samples. FNDC1, FNDC3A, FNDC3B, FNDC4, FNDC5, and GPR116 in nonaffected mucosal samples along the proximal-distal axis (-5) (a). Representative agarose gels of qRT-PCR products, including the expected amplicon lengths for each gene (b). Quantification of FNDC1, FNDC3A, FNDC3B, FNDC4, FNDC5, and GPR116 in nonaffected samples of patients with IBD () and CRC (-10) (c). Data are expressed relative to the expression in nonaffected IBD samples and normalized to the housekeeping genes ACTB and TBP. , , and .