Research Article

Demographics and Clinical and Endoscopic Characteristics of Patients with Helicobacter pylori Infection and Gastroesophageal Reflux Disease: A Case-Control Study

Table 4

(a) Endoscopic findings of GERD (insurgence and severity of esophagitis) subjects stratified according to the Helicobacter pylori (H. pylori) infection status

H. pylori status ()No esophagitis ()Esophagitis ()
Grade A ()Grade B ()Grade C ()Grade D ()

H. pylori negative ()1,559 (70.6%)379 (17.2%)216 (9.8%)43 (1.9%)12 (0.5%)
H. pylori positive ()167 (55.9%)99 (33.1%)29 (9.7%)4 (1.3%)0 (0.0%)

(b) Outcomes of subjects with GERD symptoms (insurgence of hiatal hernia) stratified according to their Helicobacter pylori infection status

H. pylori status ()No hiatal hernia ()Hiatal hernia ()

H. pylori negative ()1,530 (69.3% of H. pylori-negative subjects, 86.7% of subjects without hiatal hernia)679 (30.7% of H. pylori-negative subjects, 91.3% of subjects with hiatal hernia)
H. pylori positive ()234 (78.3% of H. pylori-positive subjects, 13.3% of subjects without hiatal hernia)65 (21.7% of H. pylori-positive subjects, 8.7% of subjects with hiatal hernia)