Gastroenterology Research and Practice

Research Article

Association of Ulcerative Colitis with FOXP3 Gene Polymorphisms and Its Colonic Expression in Chinese Patients

Table 1

Demographic characteristics of patients with ulcerative colitis (UC) and healthy controls (HC).
CharacteristicsUC patients ()HC ()
Gender (female/male)232/240270/2550.473
Age (years) ()0.768
Smoking   
 Current or ex-smoker [frequency (%)]189 (40.0)201 (38.3)0.570
 Never smoked [frequency (%)]283 (60.0)324 (61.7)
Extent of UC [frequency (%)]   
 Proctitis106 (22.5)  
 Left-sided202 (42.8)  
 Extensive164 (34.7)  
Severity of UC [frequency (%)]   
 Mild166 (35.2)  
 Moderate151 (32.0)  
 Severe155 (32.8)  
Treatment [frequency (%)]   
 Sulfasalazine/5-aminosalicylic acid379 (80.3)  
 Prednisone183 (38.8)  
 Antibiotics136 (28.8)  
 Immunosuppressive12 (2.5)  
 Colectomy10 (2.1)  
Distal colitis was defined as disease lesion distal to spleen flexure, and extensive colitis was defined as disease lesion location beyond spleen flexure.