Research Article
High Expression and Clinical Significance of Elafin in Colorectal Cancer
Table 4
Correlation of Elafin expression with clinicopathological characteristics of colorectal cancer patients.
| Clinical feature | IHC | TCGA | Total () | High (%) | Low (%) | | value | Total () | PI3 levels | | value |
| Age | | | | 0.885 | 0.347 | | | 0.086 | 0.931 | <65 | 36 | 26 (72.2) | 10 (27.8) | | | 167 | | | | ≥65 | 52 | 42 (80.8) | 10 (19.2) | | | 271 | | | | Gender | | | | 0.018 | 0.892 | | | -0.799 | 0.425 | Male | 50 | 39 (77.6) | 11 (22.4) | | | 230 | | | | Female | 38 | 29 (76.3) | 9 (23.7) | | | 208 | | | | Clinical stage | 4.849 | 0.028 | | | 0.617 | 0.537 | I-II | 41 | 36 (87.8) | 5 (12.2) | | | 248 | | | | III-IV | 47 | 32 (68.1) | 15 (31.9) | | | 190 | | | | Tumor invasive | 0.097 | 0.755 | | | -0.183 | 0.855 | T1-T3 | 64 | 50 (78.1) | 14 (21.9) | | | 384 | | | | T4 | 24 | 18 (75.0) | 6 (25.0) | | | 54 | | | | Lymph node metastasis | 3.26 | 0.071 | | | 0.390 | 0.697 | N0 | 42 | 36 (85.7) | 6 (14.3) | | | 257 | | | | N1-N2 | 46 | 32 (69.6) | 14 (30.4) | | | 281 | | | | Distant metastasis | 0.901 | 0.343 | | | 0.150 | 0.881 | M0 | 83 | 65 (78.3) | 18 (21.7) | | | 327 | | | | M1 | 5 | 3 (60.0) | 2 (40.0) | | | 64 | | | |
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Continuous variables are presented as the . IHC: immunohistochemistry; TCGA: The Cancer Genome Atlas. |