Research Article

Investigation of 23 Bile Acids in Liver Bile in Benign and Malignant Biliary Stenosis: A Pilot Study

Table 1

Serum bilirubin and C-reactive protein and bile acids in liver bile in benign and malignant biliary stenosis and controls without stenosis.

ParameterBenign stenosis ()

C.I. of mean
Median
IQR
Malignant stenosis (n)

C.I. of mean
Median
IQR
Controls without stenosis ()

C.I. of mean
Median
IQR

Serum bilirubin (μmol/L)
44.381.312.9
15.0138.015.0
11.0–49.014.5–310.011.0–49.0

C-reactive protein (mg/L)
25.728.114.2
2.510.011.0
2.0–13.35.5–57.52.8–55.0

CDCA (μmol/L)
282.411.447.4
43.82.916.6
4.5–269.70–27.90–29.5

GLCA (μmol/L)
52.628.681.9
73.012.432.1
27.2–105.80–44.74.1–260.1

GUDCA (μmol/L)
4495.4841.01528.9
192.7123.7259.2
77.4–7507.22.6–319.938.0–1247.0

GCDCA (μmol/L)
4021.11677.01616.3
6132.02642.04995.0
3027.3–10097.8308.7–5746.82404.9–9474.5

GDCA (μmol/L)
2593.1840.11383.7
1300.7381.01110.5
844.1–2995.08.9–1497.8135.9–4421.3

GCA (μmol/L)
6258.72226.71302.6
6929.03335.05354.0
2361.8–13126.0709.1–6549.52794.8–7259.0

GHCA (μmol/L)
14.78.224.1
30.18.016.4
7.7–36.32.7–14.610.3–33.8

TLCA (μmol/L)
32.518.422.5
22.35.219.3
2.5–56.90–16.82.1–77.8

TUDCA (μmol/L)
420.561.7142.6
46.819.258.9
9.5–115.30–58.89.5–152.8

TCDCA (μmol/L)
2113.5736.4528.2
1118.51734.21689.3
275.2–2301.4282.3–2319.51113.4–3290.7

TDCA (μmol/L)
772.0298.2341.3
278.8118.3377.5
30.1–1100.87.1–321.679.8–930.7

TMCA (μmol/L)
8.86.06.8
4.53.45.9
0–16.10–8.70–13.5

THCA (μmol/L)
15.117.421.5
3.811.112.1
0.9–14.83.1–35.04.0–37.2

TCA (μmol/L)
2821.61017.3643.5
1634.81658.51923.1
366.1–1906.2652.5–3343.51031.2–3048.0

CA (μmol/L)
259.614.643.7
97.802.6
5.8–465.90–20.40–17.7

Total bile acids (mmol/L)
21.814.54.8
26.765.821.9
20.5–50.043.0–87.211.2–33.0