Research Article
Investigation of 23 Bile Acids in Liver Bile in Benign and Malignant Biliary Stenosis: A Pilot Study
Table 1
Serum bilirubin and C-reactive protein and bile acids in liver bile in benign and malignant biliary stenosis and controls without stenosis.
| Parameter | Benign stenosis ()
C.I. of mean Median IQR | Malignant stenosis (n)
C.I. of mean Median IQR | Controls without stenosis ()
C.I. of mean Median IQR |
| Serum bilirubin (μmol/L) | | | | 44.3 | 81.3 | 12.9 | 15.0 | 138.0 | 15.0 | 11.0–49.0 | 14.5–310.0 | 11.0–49.0 |
| C-reactive protein (mg/L) | | | | 25.7 | 28.1 | 14.2 | 2.5 | 10.0 | 11.0 | 2.0–13.3 | 5.5–57.5 | 2.8–55.0 |
| CDCA (μmol/L) | | | | 282.4 | 11.4 | 47.4 | 43.8 | 2.9 | 16.6 | 4.5–269.7 | 0–27.9 | 0–29.5 |
| GLCA (μmol/L) | | | | 52.6 | 28.6 | 81.9 | 73.0 | 12.4 | 32.1 | 27.2–105.8 | 0–44.7 | 4.1–260.1 |
| GUDCA (μmol/L) | | | | 4495.4 | 841.0 | 1528.9 | 192.7 | 123.7 | 259.2 | 77.4–7507.2 | 2.6–319.9 | 38.0–1247.0 |
| GCDCA (μmol/L) | | | | 4021.1 | 1677.0 | 1616.3 | 6132.0 | 2642.0 | 4995.0 | 3027.3–10097.8 | 308.7–5746.8 | 2404.9–9474.5 |
| GDCA (μmol/L) | | | | 2593.1 | 840.1 | 1383.7 | 1300.7 | 381.0 | 1110.5 | 844.1–2995.0 | 8.9–1497.8 | 135.9–4421.3 |
| GCA (μmol/L) | | | | 6258.7 | 2226.7 | 1302.6 | 6929.0 | 3335.0 | 5354.0 | 2361.8–13126.0 | 709.1–6549.5 | 2794.8–7259.0 |
| GHCA (μmol/L) | | | | 14.7 | 8.2 | 24.1 | 30.1 | 8.0 | 16.4 | 7.7–36.3 | 2.7–14.6 | 10.3–33.8 |
| TLCA (μmol/L) | | | | 32.5 | 18.4 | 22.5 | 22.3 | 5.2 | 19.3 | 2.5–56.9 | 0–16.8 | 2.1–77.8 |
| TUDCA (μmol/L) | | | | 420.5 | 61.7 | 142.6 | 46.8 | 19.2 | 58.9 | 9.5–115.3 | 0–58.8 | 9.5–152.8 |
| TCDCA (μmol/L) | | | | 2113.5 | 736.4 | 528.2 | 1118.5 | 1734.2 | 1689.3 | 275.2–2301.4 | 282.3–2319.5 | 1113.4–3290.7 |
| TDCA (μmol/L) | | | | 772.0 | 298.2 | 341.3 | 278.8 | 118.3 | 377.5 | 30.1–1100.8 | 7.1–321.6 | 79.8–930.7 |
| TMCA (μmol/L) | | | | 8.8 | 6.0 | 6.8 | 4.5 | 3.4 | 5.9 | 0–16.1 | 0–8.7 | 0–13.5 |
| THCA (μmol/L) | | | | 15.1 | 17.4 | 21.5 | 3.8 | 11.1 | 12.1 | 0.9–14.8 | 3.1–35.0 | 4.0–37.2 |
| TCA (μmol/L) | | | | 2821.6 | 1017.3 | 643.5 | 1634.8 | 1658.5 | 1923.1 | 366.1–1906.2 | 652.5–3343.5 | 1031.2–3048.0 |
| CA (μmol/L) | | | | 259.6 | 14.6 | 43.7 | 97.8 | 0 | 2.6 | 5.8–465.9 | 0–20.4 | 0–17.7 |
| Total bile acids (mmol/L) | | | | 21.8 | 14.5 | 4.8 | 26.7 | 65.8 | 21.9 | 20.5–50.0 | 43.0–87.2 | 11.2–33.0 |
|
|