Research Article

Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants

Table 2

The comparison between cases with and without POH after endoscopic mucosal resection in patients with DOACs.

DOAC users POHDOAC users No POH value

Lesion number5130ā€‰
Morphology (% ())
Polypoid/nonpolypoid
80.0 (4)/20.0 (1)86.2 (112)/13.8 (18)0.69
Tumor size (mm), mean (range, min-max) (4-25) (3-30)<0.001
Rate of (% ())60.0 (3)4.6 (6)<0.001
Tumor location (% ())
Right-sided/left-sided/rectum
60.0/20.0/20.0
(3/1/1)
48.5/42.3/9.2
(63/55/12)
0.52
Histology (% ())
(SSAP/Ad/HGD/T1/others)
0/40.0/60.0/0/0
(0/2/3/0/0)
3.8/83.8/7.7/2.3/2.3
(5/109/10/3/3)
0.37
Coprescription of antiplatelet (% ())0 (0)14.6 (19)0.35

DOAC: direct oral anticoagulant; POH: postoperative hemorrhage; min: minimum; max: maximum; right-sided: cecum to transverse colon; left-sided: descending colon to sigmoid colon; SSAP: sessile serrated adenoma and polyp; Ad: low-grade adenoma; HGD: high-grade dysplasia.