Research Article

Association of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease with FADS2 rs3834458 Gene Polymorphism in the Chinese Han Population

Table 1

Comparison of clinical characteristics among the control group, the NAFLD group, and the NAFLD+CAD group.

IndicatorsControlNAFLDCAD+NAFLD

Cases (male/female)149 (75/74)113 (59/54)75 (38/37)0.927
Ages (years)0.442
BMI (kg/m2)<0.001
GLU (mmol/L)4.56 (1.11)4.84 (0.67)5.32 (1.43)<0.001
TBIL (μmol/L)0.242
ALT (U/L)17.66 (11.16)23.62 (21.20)22.63 (18.03)<0.001
AST (U/L)20.71 (6.44)21.64 (7.44)20.96 (18.43)0.141
GGT (U/L)19.59 (14.54)32.55 (27.24)25.15 (16.65)<0.001
ALP (U/L)<0.001
TG (mmol/L)1.11 (0.75)1.67 (1.17)1.46 (1.21)0.031
TC (mmol/L)<0.001
LDL-C (mmol/L)<0.001
HDL-C (mmol/L)<0.001

Control: healthy control; NAFLD: nonalcoholic fatty liver disease; NAFLD+CAD: NAFLD patients with coronary artery disease. The data of normal distribution were expressed as ; the data of nonnormal distribution were expressed as median (interquartile range). BMI: body mass index; GLU: glucose; TBIL: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: γ-glutamyl transferase; ALP: alkaline phosphatase; TG: triglyceride; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol.