Effect of the Hydroethanolic Extract of Bixa orellana Linn (Bixaceae) Leaves on Castor Oil-Induced Diarrhea in Swiss Albino Mice

Table 2

Effect of the hydroethanolic extract of Bixa orellana leaves on stool mass and stool frequencies in mice.

Group	Treatment	Total feces (g)	Diarrheal feces (g)	Inhibition (%)	Frequency (number/h)
DC	H2O (10 mL/kg)			—
Lop5	5 mg/kg			84.00
HEBo25	25 mg/kg	^b	^b	32.00	^b
HEBo50	50 mg/kg	^b	^b	56.00
HEBo100	100 mg/kg			76.00
HEBo200	200 mg/kg			88.00

Values are expressed as (). DC: diarrheal control; Lop5: Loperamide 5 mg/kg; HEBo25, HEBo50, HEBo100, and HEBo200: hydroethanolic extract of Bixa orellana leaves, respectively, at 25, 50, 100, and 200 mg/kg. Significant difference: ; compared with DC; ^b compared with Lop5.