Significance of EGFR and PTEN Expression and PLR and NLR for Predicting the Prognosis of Epithelioid Malignant Peritoneal Mesothelioma

Table 4

Univariate analyses of association of prognostic factors with overall survival of MPeM.

		No. of deaths	Median survival months (95% CI)	value
Age
<60	8	6	8 (3.32-12.68)	0.419
≥60	25	24	6 (2.76-9.24)
Sex
Female	24	22	6 (3.61-8.39)	0.856
Male	9	8	9 (0-23.61)
PTEN
Negative; Positive	26	26	4 (2.13-5.87)	0.000
	7	4	15 (8.27-21.73)
EGFR
Negative; Positive	11	9	11 (8.05-13.95)	0.045
	22	21	4 (2.28-5.72)
Asbestos
Absent	4	3	3 (0.00-9.86)	0.869
Present	29	27	6 (3.36-8.64)
PLT (10^9/L)
<300	9	7	10 (7.38-12.62)	0.214
≥300	24	23	4 (2.20-5.80)
PLR
<278	17	14	10 (7.54-12.46)	0.014
≥278	16	16	4 (2.70-5.30)
NLR
<5	16	13	9 (5.39-12.61)	0.015
≥5	17	17	4 (2.67-5.33)
LYM (10^3/μL)
<0.8	28	26	6 (2.90-9.10)	0.285
≥0.8	5	4	8 (3.71-12.29)
Ascites
Absent	6	6	10 (6.61-13.40)	0.406
Present	27	24	6 (3.50-8.50)
Clinical stage
I + II	21	18	7 (2.67-11.33)	0.036
III + IV	12	12	4 (0.61-7.40)
Chemotherapy
Yes	14	11	8 (4.73-11.27)	0.044
No	19	19	4 (1.44-6.56)