QuantiFERON-TB Gold Test Conversion Is Associated with Active Tuberculosis Development in Inflammatory Bowel Disease Patients Treated with Biological Agents: An Experience of a Medical Center in Taiwan

Table 5

Subgroup analysis of QuantiFERON-TB Gold test results before biological treatment in IBD patients.

Characteristics	Positivity ()	Negativity ()	value
Male sex, (%)	9 (90)	81 (74)	0.448
Diagnosis
CD	6 (8)	57 (80)	0.746
UC	4 (7)	53 (90)	0.746
Diagnostic mean age (years) (SD)	47.7 (15.34)	35.61 (15.54)	0.037
Mean age at biological agent (years) (SD)	53.2 (17.08)	39.63 (15.34)	0.035
BMI (kg/m^2), mean (SD)	21.58 (2.77)	22.05 (4.21)	0.637
Smoking
No smoking, (%)	4 (40)	71 (65)	0.173
Ex-smoking and current smoking, (%)	6 (60)	39 (35)
Alcohol
No drinking, (%)	7 (70)	94 (85)	0.195
Ex-drinking and current drinking, (%)	3 (30)	16 (15)
Albumin (g/dL), mean (SD)	3.96 (0.54)	4.03 (0.64)	0.702
CRP (mg/dL), mean (SD)	0.89 (0.56)	1.98 (4.26)	0.019
ESR (mm/hour), mean (SD)	22.56 (14.87)	19.4 (21.82)	0.573

BMI: body mass index; CD: Crohn’s disease; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; IBD: inflammatory bowel disease; TB: tuberculosis; UC: ulcerative colitis.