QuantiFERON-TB Gold Test Conversion Is Associated with Active Tuberculosis Development in Inflammatory Bowel Disease Patients Treated with Biological Agents: An Experience of a Medical Center in Taiwan

Table 6

Subgroup analysis of QuantiFERON-TB Gold test results after biological treatment in IBD patients.

Characteristics	Positivity ()	Negativity ()	value
Male, (%)	14 (88)	77 (73)	0.354
Diagnosis, (%)
CD	11 (16)	58 (84)	0.418
UC	5 (9)	48 (89)	0.418
Diagnostic mean age (years) (SD)	43.63 (15.8)	35.98 (16.10)	0.087
Mean age at biological agent (years) (SD)	47.88 (15.85)	39.62 (15.56)	0.066
BMI (kg/m^2), mean (SD)	21.29 (3.12)	22.07 (4.20)	0.385
Smoking
No smoking, (%)	8 (50)	71 (67)	0.296
Ex-smoking and current smoking, (%)	8 (50)	35 (33)
Alcohol
No drinking, (%)	12 (75)	90 (85)	0.297
Ex-drinking and current drinking, (%)	4 (25)	16 (15)
Albumin (g/dL), mean (SD)	3.95 (0.55)	3.95 (0.70)	0.964
CRP (mg/dL), mean (SD)	0.68 (0.77)	2.03 (4.30)	0.006
ESR (mm/hour), mean (SD)	14.50 (8.92)	22.28 (24.40)	0.030

BMI: body mass index; CD: Crohn’s disease; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; IBD: inflammatory bowel disease; TB: tuberculosis; UC: ulcerative colitis.