Research Article

Using Machine Learning to Predict Progression in the Gastric Precancerous Process in a Population from a Developing Country Who Underwent a Gastroscopy for Dyspeptic Symptoms

Table 1

Predictors ranked (variable importance) using random forest method based on sums of square error (SSE) in the training set.

Variables rankedRelative importance

Overall progression (general model)
Complete intestinal metaplasia at baseline1
Diagnosis at baseline less advanced than atrophic gastritis0.80368
Incomplete intestinal metaplasia at baseline0.64445
Depth of corpus inflammation at baseline0.43734
Alcohol intake at baseline (yes/no)0.39928
Total loss of glandular tissue at 5 months0.30324
Received anti-H. pylori treatment0.28874
Average density of polymorphonuclear cells in the antrum at baseline0.26655
Body mass index0.26324
Education level at baseline0.25006
Average density of polymorphonuclear cells in the corpus at baseline0.22872
Years of intake of proton pump inhibitors at baseline0.22002
Total depth of inflammation at baseline0.20417
Overall progression (location-specific model)
Complete intestinal metaplasia at baseline1
Diagnosis at baseline less advanced than atrophic gastritis0.72046
Incomplete intestinal metaplasia at baseline0.63149
Urinary calcium at baseline0.43548
Total loss of glandular tissue at 5 months0.41663
Depth of corpus inflammation at baseline0.40250
Depth of total inflammation from antrum/corpus at baseline0.34093
Bloating at baseline0.31531
Average density of polymorphonuclear cells in the corpus at baseline0.31494
Intake of coffee with milk at baseline0.2875
Total mucus depletion at baseline0.2635
Alcohol intake at baseline0.25981
Years of use of proton pump inhibitors0.25814
Intake of fried fava beans at baseline0.21631
Use of analgesics at baseline0.21515
Depth of total inflammation from antrum/corpus at 5 months0.18031
Antacid use at baseline0.17009
Density of H. pylori infection in the corpus and the antrum at baseline0.16174
Any reflux at baseline0.15910
Intake of fruits and vegetables at baseline0.10299