Research Article

Diagnostic and Clinical Significance of Serum Levels of D-Lactate and Diamine Oxidase in Patients with Crohn’s Disease

Table 1

General characteristics of 59 patients with CD.

CharacteristicsCD active ()CD remission () value

Age in years, mean (range)37.2 (20-47)39.6 (17-55)0.408
Sex: male, (%)13 (45)17 (57)0.363
Duration of disease in years, median (IQR)7 (2-11)7.5 (3-13)0.504
Smoking history, (%)0.626
 Current8 (27)6 (20)
 Former10 (34)9 (30)
 Never11 (38)15 (50)
Site of disease, (%)0.605
 Ileal (L1)2 (7)1(3)
 Colonic (L2)13 (45)17(57)
 Ileocolonic (L3)14 (48)12(40)
Drugs before inclusion, (%)0.450
 Mesalamine5 (17)3 (10)
 Azathioprine/6-MP7 (24)5 (17)
 Anti-TNF10 (34)9 (30)
 Anti-TNF and azathioprine/6-MP7 (24)13 (43)
Number of prior surgeries, mean (range)0.20 (0-2)0.28 (0-3)0.898
Having extraintestinal manifestations, (%)2 (6)1 (3)0.612

CD: Crohn’s disease; 6MP: 6-mercaptopurine; IQR: interquartile range. There were no significant differences between groups in the active stage CD patients and remission stage CD patients.